Journal | Blissfully Amy

What actually changes in perimenopause, and why what used to work stops working.

This is where I explain the physiology behind midlife changes in metabolism, hormones, and recovery, and what to do differently because of it.

For women who want to understand what is actually happening, not just what to do about it.

Written for the woman who wants to understand what is actually happening, not just what to do about it.

Woman resting in gym environment illustrating progressive resistance training for perimenopause metabolic health.

Why Cardio Stops Working in Perimenopause: The GLUT4 Mechanism Most Programs Miss

If your training hasn’t changed but your results have, it’s not a lack of effort. In perimenopause, declining estrogen alters how your muscles respond to insulin and training. Understanding GLUT4 and mechanical load explains why cardio stops working, and what actually replaces it.

Resistance Training and Muscle

Amy Elkhoury

5 days ago5 min read

Estrobolome in Perimenopause: The Gut Mechanism Most Approaches Ignore

The estrobolome is the gut mechanism that regulates how your body metabolises oestrogen. In perimenopause, reduced microbiome diversity disrupts this process, affecting hormonal balance, inflammation, and metabolic function.

Nutrition and Gut Health

Amy Elkhoury

Mar 273 min read

Why Everything Stops Working in Perimenopause: The Metabolic Shifts No One Explains

The habits that used to work stop working in perimenopause because your physiology has changed. This article explains what is actually happening, and why a different approach is required.

Perimenopause and Menopause Science

Amy Elkhoury

Mar 213 min read